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Science 3 November 1995:
Vol. 270. no. 5237, pp. 724 - 727
DOI: 10.1126/science.270.5237.724
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News & Comment

Robert F. Service

Drug-resistant bacteria have been on the offensive for years, with few new compounds available for a counterattack. But at a recent meeting, pharmaceutical companies introduced a promising crop of new antibiotics, with a variety of ways to beat back resistance. Whether companies have enough incentives to develop the most effective anti-resistance strategies--narrow-spectrum antibiotics--remains an open question. See sidebar (p. 725).


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Evid. Based Complement. Altern. Med.
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Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction..
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Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.
T.-W. Yu, Y. Shen, Y. Doi-Katayama, L. Tang, C. Park, B. S. Moore, C. Richard Hutchinson, and H. G. Floss (1999)
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Modulation of Endotoxin- and Enterotoxin-Induced Cytokine Release by In Vivo Treatment with beta -(1,6)-Branched beta -(1,3)-Glucan.
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Characterization of the galU Gene of Streptococcus pneumoniae Encoding a Uridine Diphosphoglucose Pyrophosphorylase: A Gene Essential for Capsular Polysaccharide Biosynthesis.
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